Paranoid psychosis in myxoedema: a case report.

Psychiatric symptoms associated with hypothyroidism are well recognised. The common mental manifestations are slowness and difficulty in apprehension, thought and action; psychomotor retardation with indecision and listlessness suggestive of a depressive syndrome.' ,2 What is perhaps less well recognised is that patients with hypothyroidism may also present with marked irritability, paranoid ideations, delusions of persecutions, and hallucinations; a picture that suggests paranoid psychosis. A number of cases were first described by Asher under the heading "myxodematous madness" .3